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Seroquel ( quetiapine ) is a prescription atypical antipsychotic that treats bipolar disorder manic episodes, depression, and schizophrenia. 1016/s0736-4679 (99)00128-6 Abstract Quetiapine (Seroquel) is a member of a new class of antipsychotic agents used in the treatment of schizophrenia. Its pharmacologic effect is primarily mediated via antagonistic binding to serotonergic (5HT2) and dopaminergic (D2) receptors. In pharmacokinetic studies in humans, quetiapine was rapidly absorbed after oral administration, with median time to reach maximum observed plasma concentration ranging from 1 to 2 hours.. Many insurance companies require a prior authorization for this drug. It is important not to stop taking Seroquel suddenly because the medication will metabolize how to get a keflex prescription from your doctor out of the body within a day. 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