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Tablet core: Microcrystalline cellulose, Croscarmellose sodium, Lactose monohydrate (see section Avelox contains lactose) and Magnesium stearate. 4 out of 10 from a total of 58 ratings for the treatment of Sinusitis. My 20 yr old daughter was given Avelox 400mg to take one per day for 7 days for a sinus infection. It totally wiped out the infection and it never came back Last night I took my first dose of Avelox 400mg. I started taking Avelox after a Z-pak didn't help my sinus infection. Since then I have had a throbbing headache on the right side of my head. After the 6th dose I called the Dr and he told me to stop taking it. It seemed to be helping my sinus infection but I was having a hard time sleeping with each dosse I took Hello and welcome to just answerAvelox is associated with muscle stiffness and pain and at times mild cramping. Hello and welcome to just answerAvelox is associated with muscle stiffness and pain and at times mild cramping. 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